Most commercial ankle-foot orthoses (AFOs) are passive structures that cannot modulate stiffness to assist with a diverse range of activities, such as stairs and ramps. It is sometimes possible to change the stiffness of passive AFOs through reassembly or benchtop adjustment, but they cannot change stiffness during use. Passive AFOs are also limited in their ankle mechanics and cannot replicate a biomimetic, nonlinear torque-angle relationship. Many research labs have developed ankle exoskeletons that show promise as viable alternatives to passive AFOs, but they face challenges with reliability, mass, and cost. Consequently, commercial translation has largely failed to date. Here we introduce the Variable Stiffness Orthosis (VSO), a quasi-passive variable stiffness ankle-foot orthosis that strikes a balance between powered and passive systems, in terms of mass, complexity, and onboard intelligence. The VSO has customizable torque-angle relationships via a cam transmission, and can make step-to-step stiffness adjustments via motorized reconfiguration of a spring support along a lead-screw. In this work, we introduce two versions: a nominal and a stiff prototype, which differ primarily in their mass and available stiffness levels. The available torque-angle relationships are measured on a custom dynamometer and closely match model predictions. The experimental results showed that the prototypes are capable of producing ankle stiffness coefficients between 9 - 330 Nm/rad.