Variants in the TERT Gene Increase the Occurrence of Solar Lentigines by Modifying Telomerase Expression Exclusively in the Skin

J Invest Dermatol. 2024 Jun;144(6):1412-1415.e7. doi: 10.1016/j.jid.2023.10.034. Epub 2023 Nov 27.
No abstract available

Keywords: Age spots; GWAS; Skin aging; Telomere length; Tissue specificity.

Publication types

  • Letter

MeSH terms

  • Female
  • Humans
  • Lentigo* / genetics
  • Lentigo* / metabolism
  • Lentigo* / pathology
  • Male
  • Skin* / metabolism
  • Skin* / pathology
  • Sunlight
  • Telomerase* / genetics
  • Telomerase* / metabolism

Substances

  • Telomerase
  • TERT protein, human