Children with asthma and eczema carrying filaggrin loss-of-function mutations have increased antibiotic use through to adulthood

Clin Exp Allergy. 2024 Apr;54(4):291-293. doi: 10.1111/cea.14440. Epub 2023 Dec 15.

Authors

Ciara Holden^{1

2}, Patrícia Soares³, Katy Fidler^{1

2}, Roger Tavendale⁴, Jessie Felton⁵, Somnath Mukhopadhyay^{1

2}

Affiliations

¹ Brighton & Sussex Medical School, Sussex, UK.
² Academic Department of Paediatrics, Royal Alexandra Children's Hospital, Brighton, UK.
³ NOVA National School of Public Health, Public Health Research Centre, Comprehensive Health Research Center, NOVA University Lisbon, Lisbon, Portugal.
⁴ Division of Population Health and Genomics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
⁵ Croydon University Hospital, Croydon, UK.

PMID: 38100258
DOI: 10.1111/cea.14440

No abstract available

Keywords: FLG loss‐of‐function mutation; antibiotics; asthma; eczema.

Publication types

Letter

MeSH terms

Asthma*
Child
Eczema* / genetics
Filaggrin Proteins
Genetic Predisposition to Disease
Genotype
Humans
Intermediate Filament Proteins / genetics
Mutation

Substances

Filaggrin Proteins
Intermediate Filament Proteins