Stress and human health in diabetes: A report from the 19th Chicago Biomedical Consortium symposium

Raghavendra G Mirmira; Rohit N Kulkarni; Pingwen Xu; Tina Drossos; Krista Varady; Kristen L Knutson; Sirimon Reutrakul; Pamela Martyn-Nemeth; Robert M Sargis; Amisha Wallia; Arleen M Tuchman; Jill Weissberg-Benchell; Kirstie K Danielson; Scott A Oakes; Celeste C Thomas; Brian T Layden; Sarah C May; Michelle Burbea Hoffmann; Eleonora Gatta; Julian Solway; Louis H Philipson

doi:10.1017/cts.2023.646

Stress and human health in diabetes: A report from the 19^th Chicago Biomedical Consortium symposium

J Clin Transl Sci. 2023 Nov 20;7(1):e263. doi: 10.1017/cts.2023.646. eCollection 2023.

Authors

Raghavendra G Mirmira¹, Rohit N Kulkarni², Pingwen Xu³, Tina Drossos⁴, Krista Varady⁵, Kristen L Knutson⁶, Sirimon Reutrakul³, Pamela Martyn-Nemeth⁷, Robert M Sargis^{3

8}, Amisha Wallia⁹, Arleen M Tuchman¹⁰, Jill Weissberg-Benchell¹¹, Kirstie K Danielson³, Scott A Oakes¹², Celeste C Thomas¹, Brian T Layden¹³, Sarah C May¹, Michelle Burbea Hoffmann¹⁴, Eleonora Gatta¹⁴, Julian Solway¹⁵, Louis H Philipson¹⁶

Affiliations

¹ Department of Medicine, Kovler Diabetes Center, The University of Chicago, Chicago, IL, USA.
² Department of Medicine, Islet Cell and Regenerative Biology, Joslin Diabetes Center, Beth Israel Deaconess Medical Center, Harvard Stem Cell Institute, Boston, MA, USA.
³ Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA.
⁴ Department of Psychiatry and Behavioral Neuroscience, Pritzker School of Medicine, The University of Chicago, Chicago, IL, USA.
⁵ Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL, USA.
⁶ Department of Neurology, Center for Circadian and Sleep Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
⁷ Department of Biobehavioral Nursing Science, University of Illinois Chicago College of Nursing, Chicago, IL, USA.
⁸ Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, Jesse Brown VA Medical Center, Chicago, IL, USA.
⁹ Department of Medicine, Division of Endocrinology, Metabolism, and Molecular Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
¹⁰ Department of History, Vanderbilt University, Nashville, TN, USA.
¹¹ Department of Psychiatry and Behavioral Sciences, Ann & Robert H. Lurie Children's Hospital of Chicago, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
¹² Department of Pathology, The University of Chicago, Chicago, IL, USA.
¹³ Section of Adult and Pediatric Endocrinology, Diabetes and Metabolism, The University of Chicago, Chicago, IL, USA.
¹⁴ Chicago Biomedical Consortium, Evanston, IL, USA.
¹⁵ Department of Medicine, University of Chicago, Chicago, IL, USA.
¹⁶ Department of Medicine and Pediatrics, Section of Adult and Pediatric Endocrinology, Diabetes and Metabolism, The University of Chicago, Chicago, IL, USA.

Abstract

Stress and diabetes coexist in a vicious cycle. Different types of stress lead to diabetes, while diabetes itself is a major life stressor. This was the focus of the Chicago Biomedical Consortium's 19^th annual symposium, "Stress and Human Health: Diabetes," in November 2022. There, researchers primarily from the Chicago area met to explore how different sources of stress - from the cells to the community - impact diabetes outcomes. Presenters discussed the consequences of stress arising from mutant proteins, obesity, sleep disturbances, environmental pollutants, COVID-19, and racial and socioeconomic disparities. This symposium showcased the latest diabetes research and highlighted promising new treatment approaches for mitigating stress in diabetes.

Keywords: Diabetes; beta cells; community; diabetes technology; healthcare; metabolic syndrome; stress.

Abstract

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