Systemic toxic effects of Mesocain® in routine surgical practice upon iatrogenic overdose requiring cardiopulmonary resuscitation - case report

Rozhl Chir. 2023;102(6):257-260. doi: 10.33699/PIS.2023.102.6.257-260.

Abstract

This case report of a patient with a traumatic head injury provides an example of a systemic toxic reaction to a local anesthetic. Clinical signs of a systemic toxic reaction and hemorrhagic shock may initially be similar: tachycardia, hypotension and unconsciousness. The purpose is thus to remind that even the treatment of a minor injury can develop into a life-threatening condition. When a skin wound is treated using suture under local or regional anesthesia, the annual incidence rate of systemic toxic reactions is 1:3,000 and that of death is 1:30,000.

Keywords: adverse events; anaphylaxis; mesocain; toxic reaction; trimecain.

Publication types

  • Case Reports

MeSH terms

  • Anesthesia, Local
  • Anesthetics, Local
  • Cardiopulmonary Resuscitation*
  • Humans
  • Iatrogenic Disease
  • Incidence

Substances

  • Anesthetics, Local