Disrupted Seasonality of Respiratory Viruses: Retrospective Analysis of Pediatric Hospitalizations in Italy from 2019 to 2023

Giordano Palmas; Sandra Trapani; Massimo Agosti; Ilaria Alberti; Maurizio Aricò; Chiara Azzari; Ilia Bresesti; Silvia Bressan; Desiree Caselli; Salvatore Cazzato; Liviana Da Dalt; Enrico Felici; Silvia Garazzino; Antonietta Giannattasio; Giovanna Iudica; Marcello Lanari; Paola Marchisio; Gaia Martelli; Gregorio Paolo Milani; Federica Soro; Emanuela Piccotti; Francesca Tirelli; Massimo Resti; Giuseppe Indolfi; Associazione Ospedali Pediatrici Italiani (AOPI) Network

doi:10.1016/j.jpeds.2024.113932

Disrupted Seasonality of Respiratory Viruses: Retrospective Analysis of Pediatric Hospitalizations in Italy from 2019 to 2023

J Pediatr. 2024 May:268:113932. doi: 10.1016/j.jpeds.2024.113932. Epub 2024 Feb 1.

Authors

Giordano Palmas¹, Sandra Trapani², Massimo Agosti³, Ilaria Alberti⁴, Maurizio Aricò⁵, Chiara Azzari², Ilia Bresesti³, Silvia Bressan⁶, Desiree Caselli⁷, Salvatore Cazzato⁸, Liviana Da Dalt⁶, Enrico Felici⁹, Silvia Garazzino¹⁰, Antonietta Giannattasio¹¹, Giovanna Iudica¹², Marcello Lanari¹³, Paola Marchisio⁴, Gaia Martelli⁸, Gregorio Paolo Milani⁴, Federica Soro¹⁴, Emanuela Piccotti¹⁵, Francesca Tirelli⁶, Massimo Resti¹⁶, Giuseppe Indolfi¹⁷; Associazione Ospedali Pediatrici Italiani (AOPI) Network

Collaborators

Associazione Ospedali Pediatrici Italiani (AOPI) Network:
Eloisa Gitto, Silvia Ricci

Affiliations

¹ Pediatric Unit, Meyer Children's Hospital IRCCS, Florence, Italy. Electronic address: giordano.palmas@meyer.it.
² Pediatric Unit, Meyer Children's Hospital IRCCS, Florence, Italy; Department of Health Sciences, University of Florence, Florence, Italy.
³ Department of Woman and Child, University of Insubria, Varese, Italy.
⁴ Pediatric Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
⁵ Pediatric Unit, S. Spirito Hospital, Azienda Sanitaria Locale, Pescara, Italy.
⁶ Department of Women's and Children's Health, University Hospital of Padova, Padua, Italy.
⁷ Pediatric Infectious Diseases Unit, Giovanni XXIII Children's Hospital, Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari, Bari, Italy.
⁸ Pediatric Unit, Department of Mother and Child Health, Salesi Children's Hospital, Ancona, Italy.
⁹ Pediatric and Pediatric Emergency Unit, Children Hospital, AO SS Antonio e Biagio e C. Arrigo, Alessandria, Italy.
¹⁰ Unit of Pediatric Infectious Diseases, University of Turin, Regina Margherita Children's Hospital, Turin, Italy.
¹¹ Pediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, Naples, Italy.
¹² Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.
¹³ Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy; Pediatric Emergency Unit, IRCCS-Policlinico Ospedaliero Universitario di Bologna, Bologna, Italy.
¹⁴ Department of Preventive Medicine, University of Brescia, Brescia, Italy.
¹⁵ Pediatric Emergency Unit, IRCCS Giannina Gaslini Institute, Genoa, Italy.
¹⁶ Pediatric Unit, Meyer Children's Hospital IRCCS, Florence, Italy.
¹⁷ Pediatric Unit, Meyer Children's Hospital IRCCS, Florence, Italy; Department of NEUROFARBA, University of Florence, Florence, Italy.

PMID: 38309520
DOI: 10.1016/j.jpeds.2024.113932

Abstract

This multicenter study in Italian hospitals highlights the epidemiologic disruptions in the circulation of the 5 main respiratory viruses from 2019 to 2023. Our data reveal a resurgence of respiratory syncytial virus and influenza during the 2022-2023 winter season, with an earlier peak in cases for both viruses, emphasizing the importance of timely monitoring.

Keywords: RSV; adenovirus; influenza; respiratory syncytial virus; rhinovirus.

Publication types

Multicenter Study

MeSH terms

Adolescent
Child
Child, Preschool
Female
Hospitalization* / statistics & numerical data
Humans
Infant
Infant, Newborn
Influenza, Human / epidemiology
Italy / epidemiology
Male
Respiratory Syncytial Virus Infections* / epidemiology
Respiratory Tract Infections* / epidemiology
Respiratory Tract Infections* / virology
Retrospective Studies
Seasons*