Desmoplasia Is Associated with Decreased Cytotoxic and Helper T Cells and Increased T-Cell Exhaustion in Cutaneous Squamous Cell Carcinoma

J Invest Dermatol. 2024 Feb 2:S0022-202X(24)00095-2. doi: 10.1016/j.jid.2024.01.019. Online ahead of print.

Authors

Affiliations

¹ Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
² Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
³ Department of Dermatology, New York University School of Medicine, New York, New York, USA.
⁴ Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA. Electronic address: cschmults@bwh.harvard.edu.

PMID: 38309575
DOI: 10.1016/j.jid.2024.01.019

No abstract available

Keywords: Cutaneous squamous cell carcinoma; Desmoplasia; Immune evasion; T-cell exclusion; T-cell exhaustion.