Methyl 1-(4-fluoro-benz-yl)-1 H-indazole-3-carboxyl-ate

Takahiro Doi; Takayuki Sakai

doi:10.1107/S2414314623009951

Methyl 1-(4-fluoro-benz-yl)-1 H-indazole-3-carboxyl-ate

IUCrdata. 2023 Nov 23;8(Pt 11):x230995. doi: 10.1107/S2414314623009951. eCollection 2023 Nov.

Authors

Takahiro Doi¹, Takayuki Sakai¹

Affiliation

¹ Osaka Institute of Public Health, Division of Hygienic Chemistry, Pharmaceutical Affairs Section, Nakamichi 1-3-3, Higashinari-ku, Osaka, 537-0025, Japan.

Abstract

The title compound, C₁₆H₁₃FN₂O₂, was synthesized by nucleophilic substitution of the indazole N-H hydrogen atom of methyl 1H-indazole-3-carboxyl-ate with 1-(bromo-meth-yl)-4-fluoro-benzene. In the crystal, some hydrogen-bond-like inter-actions are observed.

Keywords: crystal structure; intermediate compound; synthetic cannabinoid.

Grants and funding

Funding for this research was provided by: JSPS KAKENHI (grant No. 18K19719 to T. Doi; grant No. 22K10521 to T. Doi, T. Sakai).