Rivaroxaban Prophylaxis in Noncirrhotic Portal Vein Thrombosis

NEJM Evid. 2022 Dec;1(12):EVIDoa2200104. doi: 10.1056/EVIDoa2200104. Epub 2022 Nov 22.

Abstract

Rivaroxaban Prophylaxis in Noncirrhotic PVTThis trial assessed the effects of rivaroxaban on the risk of venous thromboembolism and portal hypertension-related bleeding in patients with noncirrhotic chronic portal vein thrombosis without major risk factors for thrombosis. Daily rivaroxaban use reduced the incidence of venous thromboembolism and did not increase major bleeding events.

Publication types

  • Clinical Trial

MeSH terms

  • Hemorrhage / chemically induced
  • Humans
  • Portal Vein
  • Rivaroxaban / therapeutic use
  • Venous Thromboembolism* / drug therapy
  • Venous Thrombosis* / complications

Substances

  • Rivaroxaban