Identifying Newborns with Hypoxic-Ischemic Encephalopathy in Hospital Discharge Data: A Validation Study

Anne Ego; T Debillon; D Sourd; N Mitton; J Fresson; J Zeitlin

doi:10.1016/j.jpeds.2024.113950

Identifying Newborns with Hypoxic-Ischemic Encephalopathy in Hospital Discharge Data: A Validation Study

J Pediatr. 2024 May:268:113950. doi: 10.1016/j.jpeds.2024.113950. Epub 2024 Feb 8.

Authors

Anne Ego¹, T Debillon², D Sourd³, N Mitton⁴, J Fresson⁵, J Zeitlin⁶

Affiliations

¹ Public Health Department CHU Grenoble Alpes, Univ. Grenoble Alpes, CNRS, Grenoble INP∗, TIMC-IMAG, Grenoble, France, ∗Institute of Engineering Univ, Grenoble Alpes; INSERM UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Center for Epidemiology and Statistics Sorbonne Paris Cité (CRESS), FHU PREMA, Paris Descartes University, Paris, France; Univ. Grenoble Alpes, Inserm CIC1406, CHU de Grenoble, Grenoble, France. Electronic address: aego@chu-grenoble.fr.
² Department of Neonatology CHU Grenoble Alpes, Univ. Grenoble Alpes, CNRS, Grenoble INP∗, TIMC-IMAG, Grenoble, France, ∗Institute of Engineering Univ, Grenoble Alpes.
³ Public Health Department CHU Grenoble Alpes, Univ. Grenoble Alpes, CNRS, Grenoble INP∗, TIMC-IMAG, Grenoble, France, ∗Institute of Engineering Univ, Grenoble Alpes.
⁴ Department of Bioinformatics CHU Grenoble Alpes, Univ. Grenoble Alpes, Grenoble, France.
⁵ Population Health Office, DREES, Paris, France.
⁶ INSERM UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Center for Epidemiology and Statistics Sorbonne Paris Cité (CRESS), FHU PREMA, Paris Descartes University, Paris, France.

PMID: 38336200
DOI: 10.1016/j.jpeds.2024.113950

Abstract

Hospital discharge databases (HDDs) are increasingly used for research on health of newborns. Linkage between a French population-based cohort of newborns with hypoxic-ischemic encephalopathy (HIE) and national HDD showed that the HIE ICD-10 code was not accurately reported. Our results suggest that HDD should not be used for research on neonatal HIE without prior validation of HIE ICD-10 codes.

Publication types

Validation Study
Research Support, Non-U.S. Gov't

MeSH terms

Databases, Factual*
Female
France / epidemiology
Humans
Hypoxia-Ischemia, Brain* / diagnosis
Infant, Newborn
International Classification of Diseases*
Male
Patient Discharge* / statistics & numerical data