Administration of gene therapy for haemophilia - The hub and spoke model and its regional differences and challenges

Affiliations

• ¹ Medical Clinic 2, Institute of Transfusion Medicine, University Hospital Frankfurt, Frankfurt, Germany.
• ² Haemophilia Centre, Department of Haematology, University Hospital Centre Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia.
• ³ Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free Hospital, London, UK.
• ⁴ Hemophilia Treatment Center, Department of Vascular Medicine, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands.
• ⁵ Pulmonary Hypertension & Thrombosis, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands.
• ⁶ European Haemopilia Consortium, Brussels, Belgium.
• ⁷ Hematology Department, Hospital Universitario La Paz-IdiPaz, Autonoma University, Madrid, Spain.
• ⁸ Department for Internal Medicine and Vascular Medicine, Haemophilia Treatment Center, Vivantes Hospital im Friedrichshain, Berlin, Germany.
• ⁹ Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.
• ¹⁰ Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.
• ¹¹ Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan, Italy.
• ¹² Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.