On the universality of viscosity in supersaturated binary aqueous sugar solutions: Cryopreservation by vitrification

Soledad Ruiz-Matus; Patricia Goldstein

doi:10.1016/j.cryobiol.2024.104886

On the universality of viscosity in supersaturated binary aqueous sugar solutions: Cryopreservation by vitrification

Cryobiology. 2024 Apr 4:115:104886. doi: 10.1016/j.cryobiol.2024.104886. Online ahead of print.

Authors

Soledad Ruiz-Matus¹, Patricia Goldstein²

Affiliations

¹ Department of Physics, Faculty of Science, National Autonomous University of México, 04510, Coyoacán, Ciudad de México, Mexico. Electronic address: solruiz@ciencias.unam.mx.
² Department of Physics, Faculty of Science, National Autonomous University of México, 04510, Coyoacán, Ciudad de México, Mexico. Electronic address: patricia.goldstein@ciencias.unam.

PMID: 38555011
DOI: 10.1016/j.cryobiol.2024.104886

Abstract

Nowadays, the physical nature of supersaturated binary aqueous sugar solutions in the vicinity of the glass transition represents a very important issue due to their biological applications in cryopreservation of cells and tissues, food science and stabilization and storage of nano genetic drugs. We present the construction of the Supplemented Phase Diagram and the non-equilibrium nature of the undersaturated-supersaturated kinetic transition. The description of its thermodynamic nature is achieved through the study of behavior of their viscosity as temperature is lowered and concentration increased. In this work, we find a universal character for the viscosities of several sugar water solutions.

Keywords: Cryopreservation; Glass transition; Supersaturated aqueous sugar solutions; Viscosity.

Publication types

Review