Objective: To develop a simple screening questionnaire for persistent postural-perceptual dizziness (PPPD) and evaluate its screening ability. Methods: A convenience sample of 296 individuals who met the inclusion criteria between November 2021 and January 2023 were prospectively selected for three rounds of screening at the Vertigo Specialty Clinic of the Department of Otorhinolaryngology-Head and Neck Surgery in the First Hospital of Shanxi Medical University. In conjunction with expert opinion and statistical analysis, the first and second rounds of screening were used to modify and finalize the questionnaire entries, and the third round of screening was used to evaluate the questionnaire's screening ability. Independent sample t-test was used for inter group comparison, reliability and validity indicators were employed to screen and evaluate questionnaire entries, and the receiver operating characteristic (ROC) curve was plotted to determine the optimal cut-off value and corresponding sensitivity and specificity. Results: The final PPPD screening questionnaire entries included 21 items. In evaluating the reliability of this questionnaire, the Cronbach's alpha coefficient was 0.831, the half folding coefficient was 0.742, the content validity was 0.86, and the Kaiser-Meyer-Olkin (KMO) value in the structural validity was 0.811. Additionally, there were six factors with characteristic root>1 and a cumulative contribution rate of 62.62%. The area under the ROC curve of the screening questionnaire was 0.935 (95%CI: 0.877-0.992), and the optimal cut-off value was 8.5, with a sensitivity of 85.0%, a specificity of 85.5%, and a Kappa value of 0.653. Conclusion: The PPPD simple screening questionnaire designed in this study has a high sensitivity and specificity, making it a useful tool for identifying PPPD patients.
目的： 设计一份持续性姿势-知觉性头晕（PPPD）简易筛查问卷并初步验证其筛查能力。 方法： 在山西医科大学第一医院耳鼻咽喉头颈外科眩晕专病门诊进行便利抽样，前瞻性选取2021年11月至2023年1月符合标准的受试者296例，共进行3轮筛查。第1、2轮筛查结合专家函询意见及统计分析结果，调整、确定问卷条目；第3轮筛查用于评价问卷的筛查能力。使用独立样本t检验进行组间比较，使用信度及效度指标筛选、评价问卷条目，最后绘制受试者工作特征（ROC）曲线确定cut-off值及对应的灵敏度和特异度。 结果： PPPD筛查问卷最终条目为21项。该问卷信度评价中Cronbach′s α系数为0.831，折半系数为0.742；内容效度为0.86；结构效度中Kaiser-Meyer-Olkin（KMO）值为0.811，特征根>1的因子有6个，累计贡献率为62.62%。该筛查问卷的ROC曲线下面积为0.935（95%CI：0.877~0.992），cut-off值为8.5分，灵敏度为85.0%，特异度为85.5%，Kappa值为0.653。 结论： 该研究设计的PPPD简易筛查问卷灵敏度和特异度较高，可为识别PPPD患者提供有效工具。.