Shared Decision-Making for Partial Oral Antibiotic Treatment of Infective Endocarditis: A Case Series

Sami El-Dalati; Marice Ruiz Conejo Castillo; Luke Strnad; Hassan Reda; Tessa London; Michael Sekela; Bobbi Jo Stoner

doi:10.1093/ofid/ofae166

Shared Decision-Making for Partial Oral Antibiotic Treatment of Infective Endocarditis: A Case Series

Open Forum Infect Dis. 2024 Mar 19;11(4):ofae166. doi: 10.1093/ofid/ofae166. eCollection 2024 Apr.

Authors

Sami El-Dalati¹, Marice Ruiz Conejo Castillo², Luke Strnad³, Hassan Reda⁴, Tessa London⁴, Michael Sekela⁴, Bobbi Jo Stoner⁵

Affiliations

¹ Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky Medical Center, Lexington, Kentucky, USA.
² CrescentCare, New Orleans, Louisiana, USA.
³ Division of Infectious Diseases, Department of Internal Medicine, Oregon Health and Science University, Portland, Oregon, USA.
⁴ Department of Cardiac Surgery, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
⁵ University of Kentucky College of Pharmacy, Lexington, Kentucky, USA.

Abstract

Although literature has demonstrated the noninferiority of oral antibiotics in the treatment of infectious endocarditis, widespread adoption of this practice has yet to occur in the United States. We report on 32 patients with infectious endocarditis treated by a multidisciplinary endocarditis team and a standardized approach to partial oral antibiotic therapy with a high rate of clinical success.

Keywords: clinical outcomes; endocarditis; multidisciplinary team; oral antibiotic treatment; patients who inject drugs.