Congenital and gynecological tumors: A review

Eur J Surg Oncol. 2024 Apr 16:108316. doi: 10.1016/j.ejso.2024.108316. Online ahead of print.

Abstract

Congenital tumors are rare, and malignant congenital tumors are uncommon. Benign tu,mors might be life-threatening, depending on the location and size of the tumor. Different factors affect congenital tumors, such as maternal and placental hormones and environmental factors such as drugs, radiation, and infection. Developing fetal imaging methods and continuous follow-up during pregnancy are important factors in congenital tumor prognosis. Ultrasound is the most common method used for fetal evaluation. The complementary evaluation method is MRI. Both methods are helpful and widely spread for the detection of congenital tumors. These imaging methods help the medical team make a suitable decision about therapy. Some of these tumors regressed spontaneously, and some need surgical treatments. Treatment of tumors has developed rapidly, and recently molecular-targeted drugs have been used.

Keywords: Congenital ovarian cyst; Congenital tumors; Fetal US; Molecular-targeted drugs; fetal MRI.