Novel Patterns in High-Resolution Computed Tomography in Whipple Pneumonia

Emerg Infect Dis. 2024 May;30(5):1042-1045. doi: 10.3201/eid3005.231130.

Abstract

With the use of metagenomic next-generation sequencing, patients diagnosed with Whipple pneumonia are being increasingly correctly diagnosed. We report a series of 3 cases in China that showed a novel pattern of movable infiltrates and upper lung micronodules. After treatment, the 3 patients recovered, and lung infiltrates resolved.

Keywords: China; Tropheryma whipplei; Whipple disease; Whipple pneumonia; bacteria; high-resolution computed tomography; pneumonia; respiratory infections.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • China
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Lung / diagnostic imaging
  • Lung / pathology
  • Male
  • Middle Aged
  • Pneumonia, Bacterial / diagnosis
  • Pneumonia, Bacterial / diagnostic imaging
  • Pneumonia, Bacterial / microbiology
  • Tomography, X-Ray Computed*
  • Tropheryma / genetics
  • Tropheryma / isolation & purification
  • Whipple Disease* / diagnosis
  • Whipple Disease* / diagnostic imaging
  • Whipple Disease* / drug therapy

Substances

  • Anti-Bacterial Agents