Construction of a novel near-infrared fluorescent Nile blue@MOF nanoprobe for imaging mitochondrial ATP in living cells

Analyst. 2024 May 13;149(10):2796-2800. doi: 10.1039/d4an00380b.

Abstract

A near-infrared fluorescent nanoprobe consisting of Nile blue-capped ZIF-90 is first proposed for real-time imaging of mitochondrial ATP. Owing to the strong binding of ATP with Zn2+, the structure of the probe is disrupted, leading to the release of fluorescent NB.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate* / analysis
  • Adenosine Triphosphate* / chemistry
  • Adenosine Triphosphate* / metabolism
  • Fluorescent Dyes* / chemical synthesis
  • Fluorescent Dyes* / chemistry
  • HeLa Cells
  • Humans
  • Infrared Rays
  • Mitochondria* / chemistry
  • Mitochondria* / metabolism
  • Nanoparticles / chemistry
  • Optical Imaging / methods
  • Oxazines* / chemistry

Substances

  • Nile Blue
  • Fluorescent Dyes
  • Oxazines
  • Adenosine Triphosphate