Ultrasonic mapping of midpalatal suture - An ex-vivo study

Trang H Hoang; Kim-Cuong T Nguyen; Neelambar R Kaipatur; Maria Alexiou; Thanh-Giang La; Manuel O Lagravère Vich; Paul W Major; Kumaradevan Punithakumar; Edmond H Lou; Lawrence H Le

doi:10.1016/j.jdent.2024.105024

Ultrasonic mapping of midpalatal suture - An ex-vivo study

J Dent. 2024 Apr 25:145:105024. doi: 10.1016/j.jdent.2024.105024. Online ahead of print.

Affiliations

¹ Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada.
² School of Dentistry, University of Alberta, Edmonton, AB, Canada.
³ Department of Electrical and Computing Engineering, University of Alberta, Edmonton, AB, Canada; Department of Biomedical Engineering, University of Alberta, Edmonton, AB, Canada.
⁴ Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada; School of Dentistry, University of Alberta, Edmonton, AB, Canada; Department of Biomedical Engineering, University of Alberta, Edmonton, AB, Canada; Department of Physics, University of Alberta, Edmonton, AB, Canada. Electronic address: lawrence.le@ualberta.ca.

PMID: 38670332
DOI: 10.1016/j.jdent.2024.105024

Abstract

Objective: Rapid maxillary expansion is a common orthodontic procedure to correct maxillary constriction. Assessing the midpalatal suture (MPS) expansion plays a crucial role in treatment planning to determine its effectiveness. The objectives of this preliminary investigation are to demonstrate a proof of concept that the palatal bone underlying the rugae can be clearly imaged by ultrasound (US) and the reconstructed axial view of the US image accurately maps the MPS patency.

Methods: An ex-vivo US scanning was conducted on the upper jawbones of two piglet's carcasses before and after the creation of bone defects, which simulated the suture opening. The planar images were processed to enhance bone intensity distribution before being orderly stacked to fuse into a volume. Graph-cut segmentation was applied to delineate the palatal bone to generate a bone volume. The accuracy of the reconstructed bone volume and the suture opening was validated by the micro-computed tomography (µCT) data used as the ground truth and compared with cone beam computed tomography (CBCT) data as the clinical standard. Also included in the comparison is the rugae thickness. Correlation and Bland-Altman plots were used to test the agreement between the two methods: US versus µCT/CBCT.

Results: The reconstruction of the US palatal bone volumes was accurate based on surface topography comparison with a mean error of 0.19 mm for pre-defect and 0.15 mm and 0.09 mm for post-defect models of the two samples, respectively when compared with µCT volumes. A strong correlation (R² ≥ 0.99) in measuring MPS expansion was found between US and µCT/CBCT with MADs of less than 0.05 mm, 0.11 mm and 0.23 mm for US, µCT and CBCT, respectively.

Conclusions: It was possible to axially image the MPS opening and rugae thickness accurately using high-frequency ultrasound.

Clinical significance: This study introduces an ionizing radiation-free, low-cost, and portable technique to accurately image a difficult part of oral cavity anatomy. The advantages of conceivable visualization could promise a successful clinical examination of MPS to support the predictable treatment outcome of maxillary transverse deficiency.

Keywords: 3D reconstruction; High-frequency ultrasound; Midpalatal suture; Palatal rugae; Rapid maxillary expansion.