Validity of claims-based definition of number of remaining teeth in Japan: Results from the Longevity Improvement and Fair Evidence Study

PLoS One. 2024 May 7;19(5):e0299849. doi: 10.1371/journal.pone.0299849. eCollection 2024.

Abstract

Background: Secondary healthcare data use has been increasing in the dental research field. The validity of the number of remaining teeth assessed from Japanese dental claims data has been reported in several studies, but has not been tested in the general population in Japan.

Objectives: To evaluate the validity of the number of remaining teeth assessed from Japanese dental claims data and assess its predictability against subsequent health deterioration.

Methods: We used the claims data of residents of a municipality that implemented oral health screening programs. Using the number of teeth in the screening records as the reference standard, we assessed the validity of the claims-based number of teeth by calculating the mean differences. In addition, we assessed the association between the claims-based number of teeth and pneumococcal disease (PD) or Alzheimer's disease (AD) in adults aged ≥65 years using Cox proportional hazards analyses.

Results: Of the 10,154 participants, the mean number of teeth assessed from the claims data was 20.9, that in the screening records was 20.5, and their mean difference was 0.5. During the 3-year follow-up, PD or AD onset was observed in 10.4% (3,212/30,838) and 5.3% (1,589/30,207) of participants, respectively. Compared with participants with ≥20 teeth, those with 1-9 teeth had a 1.29 (95% confidence interval [CI]: 1.17-1.43) or 1.19 (95% CI: 1.04-1.36) times higher risk of developing PD or AD, respectively.

Conclusion: High validity of the claims-based number of teeth was observed. In addition, the claims-based number of teeth was associated with the risk of PD and AD.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / epidemiology
  • Female
  • Humans
  • Japan / epidemiology
  • Longevity
  • Male
  • Oral Health
  • Tooth Loss* / epidemiology

Grants and funding

This study was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI in the form of a Grant-in-Aid for Scientific to KT [22H03299, 23K18370], the Ministry of Health, Labour and Welfare, Japan in the form of a Health Labour Sciences Research Grant to KO [23FA1022], and the the Japan Science and Technology Agency in the form of a JST FOREST Program Grant to HF [JPMJFR205J].