Atypical Pulmonary Metastasis of Prostate Adenocarcinoma: A Rare Phenomenon

Asma Jamil; Ruhma Ali; Amy Paige; Richard Miller; Nirav Mistry; Ahmed Abbas; Abu Tahir Taha

doi:10.12890/2024_004494

Atypical Pulmonary Metastasis of Prostate Adenocarcinoma: A Rare Phenomenon

Eur J Case Rep Intern Med. 2024 Apr 22;11(5):004494. doi: 10.12890/2024_004494. eCollection 2024.

Authors

Asma Jamil¹, Ruhma Ali¹, Amy Paige¹, Richard Miller¹, Nirav Mistry¹, Ahmed Abbas¹, Abu Tahir Taha²

Affiliations

¹ St Michael Medical Center, Newark, USA.
² University of California, San Francisco, USA.

Abstract

Prostate cancer can metastasise to the lung. Most common presentations described in the literature are solitary pulmonary nodules, lymphangitic spread and, rarely, pleural effusion. We describe a case of prostate adenocarcinoma with diffuse bilateral reticulonodular and lymphangitic pulmonary metastasis, and malignant pleural effusion while being on androgen deprivation therapy.

Learning points: Lymphangitic metastasis of prostate cancer to the lung with diffuse reticulonodular infiltrate is a rare presentation.In chemical castration-sensitive prostate cancer, prostate-specific antigen (PSA) levels can be improving but the patient can still develop new distant metastases.

Keywords: Prostate cancer; adenocarcinoma; lactate dehydrogenase (LDH); lymphagitic spread; metastasis; prostate-specific antigen (PSA).