Associations of variability in body mass index with cardiovascular outcomes in the general population: A systematic review

Mohammad Ali Esfandiari; Kimia Kazemzadeh; Akram Ansari; Goharsharieh Alishiri; Shaghayegh Afshari; Sepand Daliri; Mohammadreza Saleh; Sahar Balanian; Rozhina Tamannaeifar; Alireza Niazi; Fatemeh Vosoughian; Amir Abdi; Mahnaz Bakhshi Mohebbi; Reza Shah Hosseini; Elaheh Foroughi; Niloofar Deravi; Melika Arab Bafrani; Hassan Asadigandomani

doi:10.1177/20480040241234149

Associations of variability in body mass index with cardiovascular outcomes in the general population: A systematic review

JRSM Cardiovasc Dis. 2024 May 7:13:20480040241234149. doi: 10.1177/20480040241234149. eCollection 2024 Jan-Dec.

Authors

Mohammad Ali Esfandiari¹, Kimia Kazemzadeh², Akram Ansari³, Goharsharieh Alishiri⁴, Shaghayegh Afshari⁵, Sepand Daliri², Mohammadreza Saleh⁶, Sahar Balanian⁷, Rozhina Tamannaeifar⁸, Alireza Niazi⁹, Fatemeh Vosoughian¹⁰, Amir Abdi¹¹, Mahnaz Bakhshi Mohebbi¹², Reza Shah Hosseini¹³, Elaheh Foroughi¹⁴, Niloofar Deravi¹⁰, Melika Arab Bafrani¹⁵, Hassan Asadigandomani¹⁶

Affiliations

¹ Student Research Committee, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
² Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
³ Medical College, Shantou University, Shantou, Guandong, China.
⁴ Students Research Committee, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
⁵ Student Research Committee, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.
⁶ Student Research Committee, Faculty of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
⁷ University of Welfare Sciences and Social Health, Tehran, Iran.
⁸ Bioprocessing and Biodetection Laboratory, Department of Food Science and Technology, University of Tehran, Tehran, Iran.
⁹ Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran.
¹⁰ Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
¹¹ Student Research Committee, School of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
¹² Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
¹³ Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey.
¹⁴ School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
¹⁵ Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.
¹⁶ School of Medicine, Tehran University of Medical Science, Tehran, Iran.

Abstract

In today's world, high variability of body mass index (BMI) is known as a significant global health problem that can lead to many negative impacts on the cardiovascular system, including atrial fibrillation (AF) and coronary heart disease. The current systematic review aims to elucidate the effect of variability in BMI on the risk of cardiovascular outcomes. Four databases, including PubMed, Scopus, MEDLINE, and CENTRAL, were searched. All related articles up to 10 June 2022, were obtained. Titles, abstracts, and full texts were reviewed. After screening abstracts and full texts, four articles were included in our study. In these four cohort studies, 7,038,873 participants from the USA and South Korea were involved. These articles generally considered the BMI and outcomes including cardiovascular disease, AF, and coronary heart disease. All these articles reported an association between the variability of BMI and increased risk of cardiovascular outcomes. Due to the negative impact of the high variability of BMI on the risk of cardiovascular outcomes, health policymakers and practitioners should pay more attention to the significant role of BMI in health problems and physicians might better check the variability of BMI visits to visit.

Keywords: BMI; BMI variability; atrial fibrillation; cardiovascular; coronary heart disease.

Publication types

Review