Coffee consumption was associated with a lower prevalence of airflow limitation in postmenopausal women

Jui-Hung Hsu; Jia-In Lee; Shu-Pin Huang; Szu-Chia Chen; Jiun-Hung Geng

doi:10.1016/j.resinv.2024.05.002

Coffee consumption was associated with a lower prevalence of airflow limitation in postmenopausal women

Respir Investig. 2024 May 8;62(4):623-630. doi: 10.1016/j.resinv.2024.05.002. Online ahead of print.

Authors

Jui-Hung Hsu¹, Jia-In Lee², Shu-Pin Huang³, Szu-Chia Chen⁴, Jiun-Hung Geng⁵

Affiliations

¹ School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
² Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807377, Taiwan.
³ Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807377, Taiwan; Department of Urology, School of Medicine, College of Medicine, Kaohsiung Medical University 807378, Kaohsiung, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan; Environmental and Occupational Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan; Institute of Medical Science and Technology, College of Medicine, National Sun Yat-Sen University, Kaohsiung 804201, Taiwan.
⁴ Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan; Department of Internal Medicine, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University 812015, Kaohsiung, Taiwan; Division of Nephrology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807377, Taiwan; Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
⁵ Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807377, Taiwan; Department of Urology, School of Medicine, College of Medicine, Kaohsiung Medical University 807378, Kaohsiung, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan; Department of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812015, Taiwan. Electronic address: 1000596@kmuh.org.tw.

PMID: 38723441
DOI: 10.1016/j.resinv.2024.05.002

Abstract

Background: Several studies have suggested a potential correlation between menopause and airflow limitation. However, the presence of protective factors in postmenopausal women remains uncertain. Therefore, our study seeks to examine potential protective factors associated with a reduced prevalence of airflow limitation among postmenopausal women.

Methods: Postmenopausal women were recruited from the Taiwan Biobank for this cross-sectional study. Airflow limitation was defined by a forced expiratory volume in the first second (FEV1)/forced vital capacity (FVC) ratio <0.7. The participants were categorized into two groups: non-coffee drinkers and coffee drinkers, and the association between coffee consumption and airflow limitation was examined using binary logistic regression models.

Results: A total of 8149 women with available information were enrolled. Compared to the non-coffee drinkers, the coffee drinkers had a significantly lower prevalence of airflow limitation (7% vs. 5%). The odds ratio (OR) for airflow limitation was lower in the coffee drinkers than in the non-coffee drinkers (OR = 0.77; 95% confidence interval [CI] = 0.63 to 0.94) after adjusting for confounding factors. We also examined the association between daily coffee consumption in cups and airflow limitation. The women who consumed ≥2 cups of coffee per day had an OR of 0.74 (95% CI = 0.59 to 0.94) compared to those who did not consume coffee.

Conclusions: Our results suggest that habitual coffee consumption is associated with a reduction in the prevalence of airflow limitation in postmenopausal women, warranting further prospective studies to explore possible causal effects and mechanisms.

Keywords: Airflow limitation; Chronic obstructive pulmonary disease; Coffee; Epidemiologic study; Menopause; Postmenopausal hormone therapy.