Isolation, cloning and sequence analysis of the cDNA for the alpha-subunit of human chorionic gonadotropin

Nature. 1979 Oct 4;281(5730):351-6. doi: 10.1038/281351a0.

Abstract

A 621-base pair fragment of the cDNA for the alpha-subunit of human chorionic gonadotropin has been isolated by cloning in a plasmid vector, and the complete nucleotide sequence determined. The entire coding region, including the 24-amino acid pre-sequence and most of the untranslated regions, are present in the fragment.

MeSH terms

  • Base Sequence
  • Chorionic Gonadotropin / genetics*
  • Codon
  • DNA, Recombinant*
  • Female
  • Genes
  • Humans
  • Macromolecular Substances
  • Molecular Weight
  • Placenta / metabolism
  • Pregnancy
  • Protein Biosynthesis
  • Protein Precursors / genetics
  • RNA, Messenger / genetics

Substances

  • Chorionic Gonadotropin
  • Codon
  • DNA, Recombinant
  • Macromolecular Substances
  • Protein Precursors
  • RNA, Messenger

Associated data

  • GENBANK/J00149
  • GENBANK/J00150
  • GENBANK/J00151
  • GENBANK/J00152