Plasma levels of chlorimipramine and its demethyl metabolite during treatment of depression

Clin Pharmacol Ther. 1979 Nov;26(5):600-10. doi: 10.1002/cpt1979265600.
No abstract available

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Animals
  • Biological Transport
  • Brain / metabolism
  • Clomipramine / analogs & derivatives*
  • Clomipramine / blood*
  • Clomipramine / therapeutic use
  • Depression / blood
  • Depression / drug therapy*
  • Female
  • Humans
  • Hydroxyindoleacetic Acid / cerebrospinal fluid
  • Male
  • Middle Aged
  • Norepinephrine / metabolism
  • Rats
  • Serotonin / metabolism

Substances

  • Serotonin
  • Hydroxyindoleacetic Acid
  • Clomipramine
  • Norepinephrine