Antitumor activity of a folate-cleaving enzyme, carboxypeptidase G 1

Cancer Res. 1972 Oct;32(10):2114-9.
No abstract available

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology
  • Carboxypeptidases / administration & dosage
  • Carboxypeptidases / pharmacology*
  • Carboxypeptidases / therapeutic use
  • Carcinoma 256, Walker / drug therapy
  • Cell Division / drug effects
  • Cell Line
  • Cells, Cultured
  • Clone Cells
  • DNA, Neoplasm / biosynthesis
  • Deoxyuridine / metabolism
  • Depression, Chemical
  • Female
  • Folic Acid / blood
  • Folic Acid / metabolism
  • Folic Acid Deficiency / chemically induced
  • Humans
  • Injections, Intraperitoneal
  • Leukemia L1210 / drug therapy
  • Liver / metabolism
  • Lymphoma / drug therapy
  • Male
  • Mice
  • Mice, Inbred AKR
  • Mice, Inbred DBA
  • Mice, Inbred Strains
  • Neoplasms, Experimental* / drug therapy
  • Neoplasms, Experimental* / metabolism
  • Rats
  • Sarcoma 180 / drug therapy
  • Thymidine / metabolism
  • Time Factors
  • Tritium

Substances

  • Antineoplastic Agents
  • DNA, Neoplasm
  • Tritium
  • Folic Acid
  • Carboxypeptidases
  • Thymidine
  • Deoxyuridine