A comparison of behavioral and neurochemical effects of ethanol and chlordiazepoxide

Adv Exp Med Biol. 1980:132:729-37. doi: 10.1007/978-1-4757-1419-7_76.

Abstract

Many similarities were observed in the behavioral and neurochemical actions of ethanol and chlordiazepoxide (CDZ) suggesting that these agents may share common mechanisms of action. However, similarities in these actions could not be explained by effects on a benzodiazepine binding site, since only CDZ interacted with this locus.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Behavior, Animal / drug effects*
  • Brain Chemistry / drug effects*
  • Cerebellum / metabolism
  • Chlordiazepoxide / pharmacology*
  • Cyclic GMP / metabolism
  • Drinking Behavior / drug effects
  • Ethanol / pharmacology*
  • Male
  • Motor Activity / drug effects
  • Postural Balance / drug effects
  • Punishment
  • Rats

Substances

  • Ethanol
  • Chlordiazepoxide
  • Cyclic GMP