Abstract
The ATP-dependent proteolytic system present in reticulocytes can release the active hydrophilic domain of cytochrome b5 and NADH-cytochrome b5 reductase from the endoplasmic reticulum, that in mature erythrocytes act as methemoglobin reductase.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenosine Triphosphate / metabolism*
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Animals
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Cytochrome Reductases / metabolism
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Cytochrome b Group / metabolism
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Cytochrome-B(5) Reductase / metabolism*
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Cytochromes b5
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NADH, NADPH Oxidoreductases / metabolism*
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Rabbits
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Rats
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Reticulocytes / enzymology*
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Solubility
Substances
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Cytochrome b Group
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Adenosine Triphosphate
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Cytochromes b5
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NADH, NADPH Oxidoreductases
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Cytochrome Reductases
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Cytochrome-B(5) Reductase