Therapy of infected dermatitis: comparative response to two corticosteroid antimicrobial creams

J Am Acad Dermatol. 1980 Mar;2(3):207-11. doi: 10.1016/s0190-9622(80)80006-5.

Abstract

In a double-blind, parallel trial which lasted 1 week and comprised eighty-eight patients, a study of the response to topical therapy of the infected component of four common eczematous processes showed that the treatment outcome with corticosteroid antimicrobial creams was not influenced by the type of dermatitis. The cream with fluocinonide 0.05% was significantly better than the cream with triamcinolone 0.1%. Both creams were clinically superior to a cream containing only the antimicrobial agents but exerted a similar antimicrobial activity.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Double-Blind Method
  • Drug Therapy, Combination
  • Eczema / drug therapy*
  • Female
  • Fluocinolone Acetonide / analogs & derivatives*
  • Fluocinonide / administration & dosage
  • Fluocinonide / adverse effects
  • Fluocinonide / therapeutic use*
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Ointments
  • Skin Diseases, Infectious / drug therapy*
  • Triamcinolone / administration & dosage
  • Triamcinolone / adverse effects
  • Triamcinolone / therapeutic use*

Substances

  • Ointments
  • Fluocinolone Acetonide
  • Triamcinolone
  • Fluocinonide