Serum amyloid A protein in humans and four animal species: a comparison by two dimensional electrophoresis

C F Bruun; K Nordstoga; K Sletten; G Husby; G Marhaug

doi:10.1016/0305-0491(95)00074-7

Serum amyloid A protein in humans and four animal species: a comparison by two dimensional electrophoresis

Comp Biochem Physiol B Biochem Mol Biol. 1995 Oct;112(2):227-34. doi: 10.1016/0305-0491(95)00074-7.

Authors

C F Bruun¹, K Nordstoga, K Sletten, G Husby, G Marhaug

Affiliation

¹ Institute of Clinical Medicine, University of Tromsø, Norway.

PMID: 7584853
DOI: 10.1016/0305-0491(95)00074-7

Abstract

Two-dimensional electrophoresis and N-terminal analysis were used to study serum amyloid A protein (SAA) from humans, mink, fox, goat and rabbit. Previously uncharacterized SAA variants were demonstrated in fox, goat and rabbit, and considerable interspecies homology was seen. In rabbit, two novel SAAs were characterized, and SAA1 and SAA2 were demonstrated in mink and rabbit sera. The results confirm previous cDNA studies and indicate that SAA do possess an important function also in fox and goat.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Animals
Blood Proteins / analysis
Electrophoresis, Gel, Two-Dimensional
Humans
Molecular Sequence Data
Rabbits
Sequence Analysis
Serum Amyloid A Protein / analysis*
Species Specificity

Substances

Blood Proteins
Serum Amyloid A Protein