The Vogt-Koyanagi-Harada syndrome is extremely rare disease in children. The first case an 11-year-old boy presenting meningeal signs with liquor pleocytosis, bilateral swelling of optics disc, anterior uveitis and yellow-white multifocal well circumscribed lesions of chorioidea et retina has been documented by means photographs. These spots and anterior uveitis with together cephalea and grand mal paroxismus were symptoms of second case an 9-year-old boy. Disease demonstrated a decreased number of T-lymphocytes in the periferal blood of both patients. Treatment with corticosteroids was successful.