The in-vitro effect of temperature on MICs, bactericidal rates and postantibiotic effects in Staphylococcus aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa

V Magnusson; T Jonsdottir; H Gudmundsdottir; H Erlendsdottir; S Gudmundsson

doi:10.1093/jac/35.2.339

The in-vitro effect of temperature on MICs, bactericidal rates and postantibiotic effects in Staphylococcus aureus, Klebsiella pneumoniae and Pseudomonas aeruginosa

J Antimicrob Chemother. 1995 Feb;35(2):339-43. doi: 10.1093/jac/35.2.339.

Authors

V Magnusson¹, T Jonsdottir, H Gudmundsdottir, H Erlendsdottir, S Gudmundsson

Affiliation

¹ Department of Clinical Microbiology, Borgarspitalinn (Reykjavik City Hospital), Iceland.

PMID: 7759398
DOI: 10.1093/jac/35.2.339

Abstract

Varying temperatures (35.5 degrees C, 38.5 degrees C, 41 degrees C) only minimally affected growth rates in vitro of Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas aeruginosa, as well as bactericidal rates and postantibiotic effects of several antibiotics. However, MICs were reduced at least four-fold by increasing temperature in 25% of the drug-organism combinations tested.

Publication types

Comparative Study

MeSH terms

Bacteriological Techniques
Drug Resistance, Microbial*
Hot Temperature*
Klebsiella pneumoniae / drug effects*
Klebsiella pneumoniae / physiology
Microbial Sensitivity Tests
Pseudomonas aeruginosa / drug effects*
Pseudomonas aeruginosa / physiology
Staphylococcus aureus / drug effects*
Staphylococcus aureus / physiology