Serial MR after bone marrow transplantation in two patients with metachromatic leukodystrophy

AJNR Am J Neuroradiol. 1994 Nov;15(10):1929-32.

Abstract

Two children with metachromatic leukodystrophy underwent bone marrow transplantation. In both patients MR subsequently showed, first, white matter changes, then later, lack of change as the patients stabilized clinically.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Bone Marrow Transplantation / pathology*
  • Brain / pathology*
  • Child
  • Female
  • Follow-Up Studies
  • Homozygote
  • Humans
  • Leukodystrophy, Metachromatic / genetics
  • Leukodystrophy, Metachromatic / pathology
  • Leukodystrophy, Metachromatic / therapy*
  • Magnetic Resonance Imaging*
  • Male
  • Neurologic Examination