Objective: To compare carboprost trometamol with methylergometrine in managing the third stage of labor.
Method: One hundred and fifty parturient women were randomly assigned to use carboprost trometamol or methylergometrine immediately after delivery.
Result: Both the duration of the third stage and the mean blood loss were significantly less in the carboprost group than the methergine group (P < 0.001).
Conclusion: Carboprost trometamol is a more potent uterotonic drug than methylergometrine. Reducing blood loss in parturient women is very important especially in cases where there is the likelihood of anemia.