The role of fast neutron therapy in unresectable pelvic osteosarcoma: preliminary report

Med Pediatr Oncol. 1994;22(5):355-7. doi: 10.1002/mpo.2950220512.

Abstract

Primary osteosarcoma of the pelvic bones represents less than 10% of all osteosarcoma. Despite mutilating surgical procedures or high-dose radiotherapy and neoadjuvant chemotherapy, local failures and distant metastases remain common. The 2-year actuarial survival rate is less than 50% and the disease-free survival is under 20% at 2 years. We report 4 cases of pelvic osteosarcoma treated by a combination of chemotherapy, photon beam and neutron beam radiotherapy. After a median follow-up of 24 months, all 4 patients are alive and disease free.

MeSH terms

  • Adolescent
  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bone Neoplasms / drug therapy
  • Bone Neoplasms / radiotherapy*
  • Combined Modality Therapy
  • Fast Neutrons / therapeutic use*
  • Female
  • Humans
  • Male
  • Osteosarcoma / drug therapy
  • Osteosarcoma / radiotherapy*
  • Pelvic Bones*
  • Photons / therapeutic use