Dissociation of object and spatial processing domains in primate prefrontal cortex

Science. 1993 Jun 25;260(5116):1955-8. doi: 10.1126/science.8316836.

Abstract

Areas and pathways subserving object and spatial vision are segregated in the visual system. Experiments show that the primate prefrontal cortex is similarly segregated into object and spatial domains. Neurons that code information related to stimulus identity are dissociable, both by function and region, from those that code information related to stimulus location. These findings indicate that the prefrontal cortex contains separate processing mechanisms for remembering "what" and "where" an object is.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Brain Mapping
  • Haplorhini
  • Memory*
  • Neural Pathways
  • Neurons / physiology*
  • Pattern Recognition, Automated
  • Photic Stimulation
  • Prefrontal Cortex / anatomy & histology
  • Prefrontal Cortex / physiology*