Phenofibrate-induced lichenoid photodermatitis

Photodermatol Photoimmunol Photomed. 1993 Aug;9(4):156-8.

Abstract

Phenofibrate is an hypolipemiant drug derived from fibric acid. Cutaneous side effects such as pruritus, rash, urticarial lesions and some rare cases of photosensitivity have been described (1-3). The reported photosensitivity cases are clinically described as eczematous (1-3); some have been reproduced by photopatch-testing (2, 3). We studied a patient with a clinical and histopathological lichenoid eruption over light-exposed areas clearly related to phenofibrate therapy for an essential hypercholesterolemia.

Publication types

  • Case Reports

MeSH terms

  • Dermatitis, Photoallergic / etiology*
  • Dermatitis, Photoallergic / pathology
  • Female
  • Fenofibrate / adverse effects*
  • Humans
  • Middle Aged
  • Skin / pathology

Substances

  • Fenofibrate