Optimization of azathioprine therapy by measuring 6-thioguanine nucleotides and methylated mercaptopurine in renal allograft recipients

Transplant Proc. 1995 Dec;27(6):3426.

Authors

S Bergan¹, H E Rugstad, O Bentdal, G Sødal, A Hartmann, B Klemetsdal, J Aarbakke, O Stokke

Affiliation

¹ Dept of Clinical Pharmacology, National Hospital, University of Oslo, Norway.

PMID: 8540033

No abstract available

Publication types

Clinical Trial
Randomized Controlled Trial

MeSH terms

Azathioprine / administration & dosage*
Azathioprine / metabolism
Erythrocytes / metabolism
Graft Rejection / prevention & control
Guanine Nucleotides / blood*
Humans
Immunosuppressive Agents / administration & dosage*
Immunosuppressive Agents / metabolism
Kidney Transplantation*
Mercaptopurine / analogs & derivatives*
Mercaptopurine / blood
Methyltransferases / blood
Prospective Studies
Thionucleotides / blood*

Substances

Guanine Nucleotides
Immunosuppressive Agents
Thionucleotides
6-thioguanylic acid
6-methylthiopurine
Mercaptopurine
Methyltransferases
thiopurine methyltransferase
Azathioprine