[Predictivity associated with oxygen-transporting hemodynamic parameters: relation between the cardiac index and oxygen extraction]

Minerva Anestesiol. 1995 Jun;61(6):241-7.
[Article in Italian]

Abstract

Objective: To verify the predictivity of a diagram with the cardiac index (CI) on the y-axis and the oxygen extraction (O2ER) on the x-axis and to verify if the haemodynamic therapy could change the outcome.

Design: A retrospective study on a consecutive series of patients.

Setting: University Intensive Care Unit of Ancona.

Subjects: 65 critically ill patients, subdivided in survivors (38) and non survivors (27).

Interventions: All the patients have been monitored with a Swan-Ganz catheter.

Measurements: CI and O2ER at the admission (T0), at 12 (T1), 24 (T2) and 48 hours (T3) from T0. The diagram CI/02ER has been subdivided in 9 parts on the basis of the normal values of CI (> or = 2,5 and < or = 3,5 1/min/m2) and of O2ER (< or = 24 and > or = 28%).

Results: At T2 most of survivors (73.7%) is on the most favourable part of the diagram, with the CI and the O2ER normal or increased, while only 21.4% of non survivors is in this part. On the contrary only 26.3% of survivors versus 78.6% of non survivors are in the less favourable part of the diagram. The chi 2-test shows a good significantly (p = 0.003) in the different distribution on the diagram between survivors and non survivors. A 2 x 2 table has been made. We found: sensibility 78.6% specificity 73.7% and total correct 75.4%. In any other time it has been found a significant different distribution on the diagram between survivors and non survivors.

Conclusions: This diagram can be useful to predict the short term outcome in non septic patients, because at 24 hours give a correct prediction of the outcome in 3 patients on 4, with a good prediction either of the good outcome or of the exitus.

Publication types

  • English Abstract

MeSH terms

  • Body Surface Area
  • Cardiac Output*
  • Critical Illness / mortality*
  • Hemodynamics
  • Humans
  • Oxygen / blood*
  • Oxygen Consumption*
  • Predictive Value of Tests
  • Prognosis
  • Retrospective Studies
  • Sensitivity and Specificity
  • Severity of Illness Index

Substances

  • Oxygen