Multifocal motor neuropathy with conduction block and Campylobacter jejuni

Neurology. 1996 Feb;46(2):562-3. doi: 10.1212/wnl.46.2.562.

Abstract

We describe a patient with acute multifocal motor neuropathy with conduction block (MMNCB) and high titers of immunoglobulin G anti-GM1 antibodies after Campylobacter jejuni enteritis. Treatment with intravenous immune globulin led to rapid improvement with return of normal function by 6 weeks. This is the first report of C. jejuni enteritis preceding MMNCB.

Publication types

  • Case Reports

MeSH terms

  • Autoantibodies / blood
  • Campylobacter Infections / immunology
  • Campylobacter Infections / physiopathology*
  • Campylobacter jejuni* / isolation & purification
  • Feces / microbiology
  • Follow-Up Studies
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin G / immunology
  • Immunoglobulin M / blood
  • Immunoglobulin M / immunology
  • Immunoglobulins, Intravenous / therapeutic use*
  • Median Nerve / physiopathology
  • Middle Aged
  • Motor Neuron Disease / complications*
  • Motor Neuron Disease / physiopathology*
  • Motor Neuron Disease / therapy
  • Motor Neurons / physiology
  • Neural Conduction*
  • Ulnar Nerve / physiopathology

Substances

  • Autoantibodies
  • Immunoglobulin G
  • Immunoglobulin M
  • Immunoglobulins, Intravenous