Relationship of the Tufts Quantitative Neuromuscular Exam (TQNE) and the Sickness Impact Profile (SIP) in measuring progression of ALS. SSNJV/CNTF ALS Study Group

Neurology. 1996 May;46(5):1442-4. doi: 10.1212/wnl.46.5.1442.

Abstract

The Tufts Quantitative Neuromuscular Exam (TQNE) is a standardized tool for measuring muscle strength and pulmonary function in patients with amyotrophic lateral sclerosis (ALS). We describe the relationship of TQNE scores to functional disability and health-related quality of life as measured by the Sickness Impact Profile (SIP) in 524 ALS patients. There was a significant relationship (p < 0.0001) between TQNE and SIP scores, both in cross section and over time. TQNE scores strongly relate to ALS patients' quality of life and ability to perform activities of daily living.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living
  • Adult
  • Aged
  • Aged, 80 and over
  • Amyotrophic Lateral Sclerosis / physiopathology*
  • Amyotrophic Lateral Sclerosis / psychology*
  • Disability Evaluation
  • Disease Progression
  • Female
  • Humans
  • Isometric Contraction
  • Lung / physiopathology
  • Male
  • Middle Aged
  • Muscle, Skeletal / physiopathology
  • Neurologic Examination
  • Physical Examination*
  • Quality of Life*
  • Regression Analysis
  • Sickness Impact Profile*
  • Surveys and Questionnaires