Analysis of quantitative risk factors for a common oligogenic disease

Genet Epidemiol. 1995;12(6):759-64. doi: 10.1002/gepi.1370120638.

Abstract

All three simulated loci influencing the quantitative variables Q1, Q2 and Q3 were successfully mapped by using a strategy of covariate adjustment and segregation analysis, coupled with association analyses and lod-score analyses.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chromosome Mapping
  • Genetic Diseases, Inborn / genetics*
  • Genetic Markers
  • Genetic Testing / methods*
  • Genome, Human*
  • Humans
  • Linear Models
  • Linkage Disequilibrium*
  • Lod Score
  • Phenotype
  • Risk Factors

Substances

  • Genetic Markers