Abstract
Parkinsonism, tremor, chorea-ballismus, dystonia, tardive dyskinesia, myoclonus, tics and akathisia can be induced by many drugs. The drugs that are most frequently implicated in movement disorders are antipsychotics, calcium antagonists, orthopramides and substituted benzamides (e.g. metoclopramide, sulpiride, clebopride, domperidone), CNS stimulants, antidepressants, anticonvulsants, antiparkinsonian drugs and lithium. It is possible for a single drug to induce 2 or more types of movement disorders in the same patient. Movement disorders are not always reversible after drug withdrawal.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Akathisia, Drug-Induced / physiopathology
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Akathisia, Drug-Induced / prevention & control
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Anticonvulsants / adverse effects
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Antipsychotic Agents / adverse effects*
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Calcium Channel Blockers / adverse effects*
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Chorea / chemically induced
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Dyskinesia, Drug-Induced / etiology
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Dyskinesia, Drug-Induced / physiopathology
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Dyskinesia, Drug-Induced / prevention & control
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Humans
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Parkinson Disease, Secondary / chemically induced*
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Parkinson Disease, Secondary / prevention & control
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Risk Factors
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Tremor / chemically induced
Substances
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Anticonvulsants
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Antipsychotic Agents
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Calcium Channel Blockers