Fibrosarcoma in children--a rare tumour with long-term survival even with advanced disease--a report of 3 cases

Acta Oncol. 1997;36(4):438-40. doi: 10.3109/02841869709001294.

Abstract

Fibrosarcoma is a rare tumour in children. The potential of malignancy has been questioned. We present three cases of fibrosarcoma in children . The follow-up periods range from 10 to 37 years. The first patient had pulmonary metastases at the time of diagnosis in 1958. The primary tumour in fossa ischio-rectalis was resected in 1960. Lung metastases were resected in 1960 and 1989. Radiotherapy was given in 1992. He is still alive with metastases 37 years after the first manifestation of disease. The second patient had a primary tumour and several local recurrences in the mandible. He is alive without evidence of disease 4 years after resection of pulmonary metastases and 21 years after resection of the primary tumour. The third patient has no signs of recurrence or metastatic spread 10 years after a wide excision of subcutaneous tumours of the left upper arm. The cases demonstrate a special tumour-entity of low-grade malignancy, which show a good prognosis and a wide spectrum of biological behaviour.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Neoplasms / pathology
  • Abdominal Neoplasms / surgery
  • Adolescent
  • Child, Preschool
  • Disease-Free Survival
  • Fibrosarcoma / pathology*
  • Fibrosarcoma / secondary
  • Fibrosarcoma / surgery
  • Follow-Up Studies
  • Humans
  • Infant
  • Lung Neoplasms / secondary
  • Lung Neoplasms / surgery
  • Male
  • Mandibular Neoplasms / pathology
  • Mediastinal Neoplasms / secondary
  • Mitosis
  • Muscle Neoplasms / pathology
  • Neoplasm Recurrence, Local / pathology
  • Survival Rate
  • Vimentin / analysis

Substances

  • Vimentin