12,13-isotaxanes: synthesis of new potent analogs and X-ray crystallographic confirmation of structure

J Med Chem. 1997 Aug 29;40(18):2810-2. doi: 10.1021/jm9703350.
No abstract available

MeSH terms

  • Alkaloids / chemical synthesis
  • Alkaloids / chemistry
  • Alkaloids / toxicity
  • Animals
  • Antineoplastic Agents / chemical synthesis
  • Antineoplastic Agents / chemistry*
  • Antineoplastic Agents / toxicity
  • Bridged-Ring Compounds / chemical synthesis
  • Bridged-Ring Compounds / chemistry*
  • Crystallography, X-Ray
  • Female
  • Humans
  • Melanoma, Experimental / drug therapy
  • Mice
  • Mice, Inbred Strains
  • Molecular Conformation
  • Molecular Structure
  • Ovarian Neoplasms
  • Paclitaxel / analogs & derivatives*
  • Paclitaxel / chemical synthesis
  • Paclitaxel / chemistry*
  • Paclitaxel / toxicity
  • Taxoids*
  • Tumor Cells, Cultured

Substances

  • Alkaloids
  • Antineoplastic Agents
  • Bridged-Ring Compounds
  • Taxoids
  • taxane
  • Paclitaxel