Abstract
Aspects of motor neuron diseases in man are described and compared with a series of animal models for these disorders. Such models provide new approaches to understanding many features of abnormalities of the central and peripheral nervous system.
MeSH terms
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Amyotrophic Lateral Sclerosis / physiopathology
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Animals
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Anterior Horn Cells / pathology
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Axonal Transport
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Dogs
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Humans
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Mice
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Mice, Neurologic Mutants / anatomy & histology
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Mice, Neurologic Mutants / genetics
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Mice, Neurologic Mutants / physiology*
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Motor Neurons / physiology*
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Nerve Degeneration
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Neuromuscular Diseases / complications
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Neuromuscular Diseases / pathology
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Neuromuscular Diseases / physiopathology*
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Spinal Cord / pathology
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Virus Diseases / complications