Neuropsychological deficits in HIV-1 seropositive and seronegative intravenous drug users (IVDUs): a follow-up study

J Int Neuropsychol Soc. 1996 Mar;2(2):126-33. doi: 10.1017/s1355617700000977.

Abstract

Human immunodeficiency virus type 1 (HIV-1) seropositive AIDS free and HIV-1 seronegative intravenous drug users were tested twice with a comprehensive neuropsychological test battery. Only minor group differences were found. Memory difficulties were the most pronounced difference with lower scores in the HIV-1 seropositive group. The memory difficulties were to some degree associated with emotional difficulties, that is, anxiety. The HIV-1 seropositive subjects were tested a third time and there was no further decline in any test with memory content at this testing. The only test that showed a significant decline in the HIV-1 seropositive group was the Trail Making Test.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • AIDS Dementia Complex / diagnosis*
  • AIDS Dementia Complex / psychology
  • Adult
  • Arousal
  • Female
  • Follow-Up Studies
  • HIV Seronegativity*
  • HIV Seropositivity / diagnosis*
  • HIV Seropositivity / psychology
  • HIV-1*
  • Humans
  • Male
  • Mental Recall
  • Neuropsychological Tests*
  • Substance Abuse, Intravenous / psychology*