Protein engineering aspartic proteinases. Site-directed mutagenesis, biochemical characterisation, and X-ray analysis of chymosins with substituted single amino acid substitutions and loop replacements

Adv Exp Med Biol. 1998:436:169-77.

Authors

A Albert¹, T L Blundell, V Dhanaraj, L E Donate, M Groves, K Guruprasad, P G Nugent, P Orprayoon, J E Pitts, S Rufino, N Srinivasan, M Williams, J Wilsher

Affiliation

¹ Department of Crystallography, Birkbeck College, University of London, United Kingdom.

PMID: 9561215

No abstract available

Publication types

Review

MeSH terms

Amino Acids
Animals
Chymosin / chemistry*
Chymosin / genetics*
Crystallography, X-Ray
Gene Expression
Mutagenesis, Site-Directed
Protein Engineering / methods*
Protein Structure, Secondary*
Recombinant Fusion Proteins / chemistry
Recombinant Fusion Proteins / genetics

Substances

Amino Acids
Recombinant Fusion Proteins
Chymosin