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No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease.
Wavrant-DeVrièze F, Rudrasingham V, Lambert JC, Chakraverty S, Kehoe P, Crook R, Amouyel P, Wu W, Holmans P, Rice F, Pérez-Tur J, Frigard B, Morris JC, Carty S, Cottel D, Tunstall N, Lovestone S, Petersen RC, Chartier-Harlin MC, Goate A, Owen MJ, Williams J, Hardy J. Wavrant-DeVrièze F, et al. Among authors: williams j. Neurosci Lett. 1999 Mar 5;262(2):137-9. doi: 10.1016/s0304-3940(99)00035-x. Neurosci Lett. 1999. PMID: 10203250
Genetic variability at the amyloid-beta precursor protein locus may contribute to the risk of late-onset Alzheimer's disease.
Wavrant-De Vrièze F, Crook R, Holmans P, Kehoe P, Owen MJ, Williams J, Roehl K, Lahiri DK, Shears S, Booth J, Wu W, Goate A, Chartier-Harlin MC, Hardy J, Pérez-Tur J. Wavrant-De Vrièze F, et al. Among authors: williams j. Neurosci Lett. 1999 Jul 9;269(2):67-70. doi: 10.1016/s0304-3940(99)00417-6. Neurosci Lett. 1999. PMID: 10430506
A novel Alzheimer disease locus located near the gene encoding tau protein.
Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH Jr, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L; IGAP Consortium; Haines JL, Psaty BM, Van … See abstract for full author list ➔ Jun G, et al. Among authors: williams j. Mol Psychiatry. 2016 Jan;21(1):108-17. doi: 10.1038/mp.2015.23. Epub 2015 Mar 17. Mol Psychiatry. 2016. PMID: 25778476 Free PMC article.
Presenilin-1 polymorphism and Alzheimer's disease.
Owen MJ, Kehoe P, Williams J. Owen MJ, et al. Among authors: williams j. Lancet. 1996 Aug 10;348(9024):414. doi: 10.1016/s0140-6736(05)65041-6. Lancet. 1996. PMID: 8709769 No abstract available.
Genetic studies on chromosome 12 in late-onset Alzheimer disease.
Wu WS, Holmans P, Wavrant-DeVrièze F, Shears S, Kehoe P, Crook R, Booth J, Williams N, Pérez-Tur J, Roehl K, Fenton I, Chartier-Harlin MC, Lovestone S, Williams J, Hutton M, Hardy J, Owen MJ, Goate A. Wu WS, et al. Among authors: williams n, williams j. JAMA. 1998 Aug 19;280(7):619-22. doi: 10.1001/jama.280.7.619. JAMA. 1998. PMID: 9718053
A full genome scan for late onset Alzheimer's disease.
Kehoe P, Wavrant-De Vrieze F, Crook R, Wu WS, Holmans P, Fenton I, Spurlock G, Norton N, Williams H, Williams N, Lovestone S, Perez-Tur J, Hutton M, Chartier-Harlin MC, Shears S, Roehl K, Booth J, Van Voorst W, Ramic D, Williams J, Goate A, Hardy J, Owen MJ. Kehoe P, et al. Among authors: williams n, williams h, williams j. Hum Mol Genet. 1999 Feb;8(2):237-45. doi: 10.1093/hmg/8.2.237. Hum Mol Genet. 1999. PMID: 9931331
Alpha-2 macroglobulin gene and Alzheimer disease.
Rudrasingham V, Wavrant-De Vrièze F, Lambert JC, Chakraverty S, Kehoe P, Crook R, Amouyel P, Wu W, Rice F, Pérez-Tur J, Frigard B, Morris JC, Carty S, Petersen R, Cottel D, Tunstall N, Holmans P, Lovestone S, Chartier-Harlin MC, Goate A, Hardy J, Owen MJ, Williams J. Rudrasingham V, et al. Among authors: williams j. Nat Genet. 1999 May;22(1):17-9; author reply 21-2. doi: 10.1038/8726. Nat Genet. 1999. PMID: 10319854 No abstract available.
Susceptibility locus for Alzheimer's disease on chromosome 10.
Myers A, Holmans P, Marshall H, Kwon J, Meyer D, Ramic D, Shears S, Booth J, DeVrieze FW, Crook R, Hamshere M, Abraham R, Tunstall N, Rice F, Carty S, Lillystone S, Kehoe P, Rudrasingham V, Jones L, Lovestone S, Perez-Tur J, Williams J, Owen MJ, Hardy J, Goate AM. Myers A, et al. Among authors: williams j. Science. 2000 Dec 22;290(5500):2304-5. doi: 10.1126/science.290.5500.2304. Science. 2000. PMID: 11125144
Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease.
Sims R, Hollingworth P, Moskvina V, Dowzell K, O'Donovan MC, Powell J, Lovestone S, Brayne C, Rubinsztein D, Owen MJ, Williams J, Abraham R. Sims R, et al. Among authors: williams j. Neurosci Lett. 2009 Sep 11;461(1):54-9. doi: 10.1016/j.neulet.2009.05.051. Epub 2009 May 27. Neurosci Lett. 2009. PMID: 19477230
We genotyped 11 SNPs in OLIG2 previously tested for association with schizophrenia [L. Georgieva, V. Moskvina, T. Peirce, N. Norton, N.J. Bray, L. Jones, P. Holmans, S. Macgregor, S. Zammit, J. Wilkinson, H. Williams, I. Nikolov, N. Williams, D. Ivanov …
We genotyped 11 SNPs in OLIG2 previously tested for association with schizophrenia [L. Georgieva, V. Moskvina, T. Peirce, N. Norton, N.J …
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