Habashita H - Search Results

1

Potent, low-molecular-weight non-peptide inhibitors of malarial aspartyl protease plasmepsin II.

Haque TS, Skillman AG, Lee CE, Habashita H, Gluzman IY, Ewing TJ, Goldberg DE, Kuntz ID, Ellman JA. Haque TS, et al. Among authors: habashita h. J Med Chem. 1999 Apr 22;42(8):1428-40. doi: 10.1021/jm980641t. J Med Chem. 1999. PMID: 10212129

2

Novel and potent anti-malarial agents.

Brinner KM, Mi Kim J, Habashita H, Gluzman IY, Goldberg DE, Ellman JA. Brinner KM, et al. Among authors: habashita h. Bioorg Med Chem. 2002 Nov;10(11):3649-61. doi: 10.1016/s0968-0896(02)00207-9. Bioorg Med Chem. 2002. PMID: 12213481

3

Design, synthesis, and biological evaluation of the combinatorial library with a new spirodiketopiperazine scaffold. Discovery of novel potent and selective low-molecular-weight CCR5 antagonists.

Habashita H, Kokubo M, Hamano S, Hamanaka N, Toda M, Shibayama S, Tada H, Sagawa K, Fukushima D, Maeda K, Mitsuya H. Habashita H, et al. J Med Chem. 2006 Jul 13;49(14):4140-52. doi: 10.1021/jm060051s. J Med Chem. 2006. PMID: 16821774

4

Spirodiketopiperazine-based CCR5 antagonists: Lead optimization from biologically active metabolite.

Nishizawa R, Nishiyama T, Hisaichi K, Matsunaga N, Minamoto C, Habashita H, Takaoka Y, Toda M, Shibayama S, Tada H, Sagawa K, Fukushima D, Maeda K, Mitsuya H. Nishizawa R, et al. Among authors: habashita h. Bioorg Med Chem Lett. 2007 Feb 1;17(3):727-31. doi: 10.1016/j.bmcl.2006.10.084. Epub 2006 Nov 1. Bioorg Med Chem Lett. 2007. PMID: 17118654

5

Structure-activity relationship studies of sphingosine-1-phosphate receptor agonists with N-cinnamyl-β-alanine moiety.

Kurata H, Otsuki K, Kusumi K, Kurono M, Terakado M, Seko T, Mizuno H, Ono T, Hagiya H, Minami M, Nakade S, Habashita H. Kurata H, et al. Among authors: habashita h. Bioorg Med Chem Lett. 2011 Mar 1;21(5):1390-3. doi: 10.1016/j.bmcl.2011.01.029. Epub 2011 Jan 11. Bioorg Med Chem Lett. 2011. PMID: 21295477

6

Structure-activity relationship studies of S1P agonists with a dihydronaphthalene scaffold.

Kurata H, Kusumi K, Otsuki K, Suzuki R, Kurono M, Tokuda N, Takada Y, Shioya H, Mizuno H, Komiya T, Ono T, Hagiya H, Minami M, Nakade S, Habashita H. Kurata H, et al. Among authors: habashita h. Bioorg Med Chem Lett. 2012 Jan 1;22(1):144-8. doi: 10.1016/j.bmcl.2011.11.048. Epub 2011 Nov 20. Bioorg Med Chem Lett. 2012. PMID: 22153936

7

Design and synthesis of novel metalloproteinase inhibitors.

Nakatani S, Ikura M, Yamamoto S, Nishita Y, Itadani S, Habashita H, Sugiura T, Ogawa K, Ohno H, Takahashi K, Nakai H, Toda M. Nakatani S, et al. Among authors: habashita h. Bioorg Med Chem. 2006 Aug 1;14(15):5402-22. doi: 10.1016/j.bmc.2006.03.032. Epub 2006 Apr 18. Bioorg Med Chem. 2006. PMID: 16621578

8

Discovery of a new chemical lead for a matrix metalloproteinase inhibitor.

Ikura M, Nakatani S, Yamamoto S, Habashita H, Sugiura T, Takahashi K, Ogawa K, Ohno H, Nakai H, Toda M. Ikura M, et al. Among authors: habashita h. Bioorg Med Chem. 2006 Jun 15;14(12):4241-52. doi: 10.1016/j.bmc.2006.01.059. Epub 2006 Feb 14. Bioorg Med Chem. 2006. PMID: 16481176

9

Discovery of S1P agonists with a dihydronaphthalene scaffold.

Kurata H, Kusumi K, Otsuki K, Suzuki R, Kurono M, Takada Y, Shioya H, Komiya T, Mizuno H, Ono T, Hagiya H, Minami M, Nakade S, Habashita H. Kurata H, et al. Among authors: habashita h. Bioorg Med Chem Lett. 2011 Jul 1;21(13):3885-9. doi: 10.1016/j.bmcl.2011.05.029. Epub 2011 May 15. Bioorg Med Chem Lett. 2011. PMID: 21641216

10

Discovery of ONO-8590580: A novel, potent and selective GABA_A α₅ negative allosteric modulator for the treatment of cognitive disorders.

Lewis A, Beresford A, Chambers MS, Clark G, Hartley DC, Hirst KL, Higashino M, Kawahadara S, Nakanishi M, Saito T, Imagawa A, Habashita H, Maidment S, Macleod AM, Owens AP, Rae A, Rouse C, Wishart G. Lewis A, et al. Among authors: habashita h. Bioorg Med Chem Lett. 2020 Nov 15;30(22):127536. doi: 10.1016/j.bmcl.2020.127536. Epub 2020 Sep 6. Bioorg Med Chem Lett. 2020. PMID: 32898695

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