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An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes.
Lefebvre V, Zhou G, Mukhopadhyay K, Smith CN, Zhang Z, Eberspaecher H, Zhou X, Sinha S, Maity SN, de Crombrugghe B. Lefebvre V, et al. Among authors: zhang z. Mol Cell Biol. 1996 Aug;16(8):4512-23. doi: 10.1128/MCB.16.8.4512. Mol Cell Biol. 1996. PMID: 8754852 Free PMC article.
Sox9 is required for cartilage formation.
Bi W, Deng JM, Zhang Z, Behringer RR, de Crombrugghe B. Bi W, et al. Among authors: zhang z. Nat Genet. 1999 May;22(1):85-9. doi: 10.1038/8792. Nat Genet. 1999. PMID: 10319868
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